MacroGenics, Inc. (MGNX)

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MacroGenics announced positive interim results for MGC026, showing a 27% overall response rate in heavily pretreated SCCHN patients. This suggests potential effectiveness for a challenging patient group and sets the stage for a front-line combination study with pembrolizumab. The manageable safety profile adds to the optimism around MGC026's future in cancer treatment.

Updated about 21 hours ago

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MacroGenics Announces Positive Interim Phase 1 Results for MGC026 and Highlights Plans to Initiate Front-Line Combination Study in SCCHN

MacroGenics Announces Positive Interim Phase 1 Results for MGC026 and Highlights Plans to Initiate Front-Line Combination Study in SCCHN

1 day ago

MacroGenics Announces Positive Interim Phase 1 Results for MGC026 and Highlights Plans to Initiate Front-Line Combination Study in SCCHN

Durable responses observed across multiple tumor types during dose escalationMGC026 demonstrated 27% best overall response rate (6/22 patients; 4 confirmed and 2 unconfirmed PRs) in heavily pretreated SCCHN patientsMGC026 demonstrated manageable safety and tolerability profile with no treatment-related discontinuations in SCCHN patientsPlan to initiate front-line SCCHN cohort evaluating MGC026 in combination with pembrolizumab ROCKVILLE, MD, Oct. 23, 2026 (GLOBE NEWSWIRE) -- MacroGenics, Inc. (N

1 day ago

MacroGenics Announces Phase 1 MGC026 Delivers 27% Response Rate In SCCHN, Showing Durable Tumor Activity And Advancing Toward Front-Line Pembrolizumab Combination Trial

Durable responses observed across multiple tumor types during dose escalationMGC026 demonstrated 27% best overall response rate (6/22 patients; 4 confirmed and 2 unconfirmed PRs) in heavily pretreated SCCHN

2 days ago

MacroGenics Says First Patient Dosed in Phase 1 Study of MGC030 for Advanced Solid Tumors

MacroGenics Says First Patient Dosed in Phase 1 Study of MGC030 for Advanced Solid Tumors

9 days ago